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Search Results for " glyoxalase i "

Targets Recommended: Others

13

抑制剂 & 化合物

1

天然产物

1

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T11433	Glyoxalase I inhibitor	Others	Others
	Glyoxalase I inhibitor, a candidate for anticancer agents, is a potent Glyoxalase I (GLO1) inhibitor.
T11432	Glyoxalase I inhibitor free base	Others	Others
	Glyoxalase I inhibitor (free base), a candidate for anticancer agents, is a potent Glyoxalase I (GLO1) inhibitor.
T64023	Glyoxalase I inhibitor 4
	Glyoxalase I inhibitor 4 是乙二醛酶 I (GLO1) 的有效抑制剂 (Ki: 10 nM)。
T64153	Glyoxalase I inhibitor 1
	Glyoxalase I inhibitor 1 是 glyoxalase I (GLO1) 的有效抑制剂 (IC50: 26 nM)。
T62699	Glyoxalase I inhibitor 2
	Glyoxalase I inhibitor 2 (compound 26) 是一种 glyoxalase I (GLO1) 的有效抑制剂 (IC50: 0.5 μM)。Glyoxalase I inhibitor 2 具有潜力进行抑郁和焦虑的研究。
T61103	Glyoxalase I inhibitor 5
	Glyoxalase I inhibitor 5 (Compound 9h) is a potent inhibitor of glyoxalase I (Glo-I), with an IC50 value of 1.28 μM. This compound holds promise as an anticancer agent [1].
T61534	Glyoxalase I inhibitor 3
	Glyoxalase I inhibitor 3 (compound 22g) 是一种有效的乙二醛酶 I (GLO1)抑制剂，IC50为 0.011 μM。Glyoxalase I inhibitor 3具有研究抑郁和焦虑的潜力。
T61286	Glyoxalase I inhibitor 7
	Glyoxalase I inhibitor 7 (Compound 6) is a potent inhibitor of glyoxalase I (Glo-I) with an IC50 of 3.65 μM. It exhibits potential as an anticancer agent [1].
T61692	Glyoxalase I inhibitor 6
	Glyoxalase I inhibitor 6 (Compound 9j) is an inhibitor of glyoxalase I (Glo-I) with an IC50 value of 1.13 μM. This compound shows potential as an anticancer agent, demonstrating low toxicity [1].
T63944	4BAB
	4BAB (compound 29) 是一种乙二醛酶 I (GLO1) 的不可逆抑制剂，表现出抗癌活性。
T71762	TLSC702
	TLSC702 is a novel Inhibitor of Human Glyoxalase I, Inducing Apoptosis in Tumor Cells.
T80098	N,S-Bis-Fmoc-Glutathione
	N,S-Bis-Fmoc-Glutathione为一有效glyoxalase II抑制剂，其Ki值达0.32 mM。
T8424	TLK117 TER117	Others	Others
	TLK117 selective inhibits Glutathione S-transferase P1–1 (GSTP1-1)(Ki of 0.4 μM for GSTP).

化合物

Glyoxalase I inhibitor

Cat.No: T11433

Target: Others

Glyoxalase I inhibitor free base

Cat.No: T11432

Target: Others

Glyoxalase I inhibitor 4

Cat.No: T64023

Glyoxalase I inhibitor 1

Cat.No: T64153

Glyoxalase I inhibitor 2

Cat.No: T62699

Glyoxalase I inhibitor 5

Cat.No: T61103

Glyoxalase I inhibitor 3

Cat.No: T61534

Glyoxalase I inhibitor 7

Cat.No: T61286

Glyoxalase I inhibitor 6

Cat.No: T61692

Cat.No: T63944

Cat.No: T71762

N,S-Bis-Fmoc-Glutathione

Cat.No: T80098

Cat.No: T8424

Synonym: TER117

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
TN4308	Isolupalbigenin	Antifection	Microbiology/Virology
	Isolupalbigenin shows promising cytotoxic effects toward HL-60 cells (IC50 4.3 ± 0.7 to 18.0 ± 1.7 uM), it also shows in vitro inhibitory activity toward human glyoxalase I. Isolupalbigenin shows two different antibacterial activities against MRSA: direct growth inhibition and intensification of methicillin sensitivity, it could lead to the development of compounds for new approaches against MRSA infection.

天然产物

Isolupalbigenin

Cat.No: TN4308

Target: Antifection

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-01618	GLO1 Protein, Mouse, Recombinant (His) glyoxalase I,Glo-1r,GLY1,Glo1-r,2510049H23...	Mouse	E. coli
	Lactoylglutathione lyase, also known as Methylglyoxalase, Aldoketomutase, Glyoxalase I, Ketone-aldehyde mutase, S-D-lactoylglutathione methylglyoxal lyase and GLO1, is a member of the glyoxalase I family. GLO1 / Glyoxalase I is a ubiquitous cellular defense enzyme involved in the detoxification of methylglyoxal, a cytotoxic byproduct of glycolysis. Accumulative evidence suggests an important role of GLO1 expression in protection against methylglyoxal-dependent protein adduction and cellul...

重组蛋白

GLO1 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-01618

Species: Mouse

Expression System: E. coli

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